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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e35eb8cac623380b2539a2c96cf7e5d1af2724a43bdedf86515a3cb53c050aa' 
  AND token = 'nUK/fXZs/va2sC3Daiv2BbG1YuKIwonFc9Qb3qbGmsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}