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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5e6566b7c3ebc82977ad8e64734a4ac3d8e3f1aa62043af4b2c26c26a9a2f52' 
  AND token = '4Jpm7z/5nwm3ny45ej/NzL3XOdiI7rz3wwfihNDsQ8w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}