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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ac2c129afb83c12f9afd62a5f608386d24b5ae5adb3d4026d36944f36ca11cd' 
  AND token = 'jEHley5QiTnGuOiCfTLh09PHClpveWtC1XulS4Bi+gw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}