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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0cbc535193414d9823097c14ae168cb4c6f616031d334873b5fce2b83cd3194' 
  AND token = 'Mz4kB0ymKNw/nnPcWmg+SV8XLHI2VaDIQyE4JJNR/4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}