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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e46ab957ee786ce6e2c86dc18e4c801d562c194b3c78e72ac732d8a0e4439f2a' 
  AND token = 'dgs50qJ0C9OLjvTOuO4B6q4EhctZpe5kxQKVb9ZS0Gc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}