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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2fe484f8d5e0c0deca3873f9491409d20d5313a09153ef4a7afb963b0484e57' 
  AND token = 'G5QJ6SGh1kHZQsDuPa+o8SYVD4atBdf5JsVxHqRxgzg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}