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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc5feacb409cbc11488e003f1dba7d8b87e87585dfa23b32d55d36cf7816b2bc' 
  AND token = 'SKM/mcE1APJxC6x3OdBLz6f6AnMHmXBVtd7GMXPdBwo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}