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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b68df0a8d24d4ec3b77076b2ec3bdf9514101d577e8c2c8dce1901ecf1de545' 
  AND token = 'pHHm/9RCwRPyJfUcwJzzsDzYvSn7hsBcGuG1wXEttSo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}