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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1650cabc15246b9d877be7de961aa2595e8087438d97341e318d1a70ed4d7554' 
  AND token = 'VJlO9hUsCWhXBQi2JVf2G/6jnQXk1CeixMJ/tQmu2Nc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}