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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54b94c588625dd59667a303ee9ea56e68aa3068c226d2cd85929160a56c06378' 
  AND token = 'avR/OYpkNrxX0nhp+ChRPL5vp2jO+yIAYkpdaaM9bfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}