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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '218d5156d94ebb1548c005672f4a7ae41a18ec7cdaf034d1c1b595547702a85b' 
  AND token = '4dGWXkOuVeazBKGyHkE8BOmccQFWSpSeqNwj0XldhEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}