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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '443da7b2e8055c8b3a4bda152d659e224beb36d5cb4e0d5e67b2b8b9f16c17d6' 
  AND token = '+43VyarQFboQ7+YRt+aymOCC2tFSETNdYB2PVGAn/Q8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}