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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '352e725daebac70c1f5362df690ff03d0970ad2236376829f3d1a35a47e06c4f' 
  AND token = 'ARHb6sNuBehJmyPdyafM+DY1HC7DTtJUSOZogWB96Y8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}