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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fefc5fa54e035a09d054c011dff6e5e9c7d5de9f18d610e4afb058f6c813f690' 
  AND token = 'd93zDic2XPo1DGZmMvZ61r+FMmKR9EWX/SSOhHfuDm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}