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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2117a18d4a96a9b0e69205eec6576d564d782ae6023f8186b4a256103f84564d' 
  AND token = 'w7JuLuepZL8Yju1TZKeFgFQeqf5ibrRYZFCwkBqRnZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}