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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ca5414821b92d67f877d37afb2d75b9006a0cd8fbb1c634e33302bc212c6ee0' 
  AND token = 'GWlxnwYCa2ab+1hpx8dueXy0logJ7zXSHE25Jvu3SRg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}