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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c548bde878f99e6dda4a7524f61cda953d5e79e851584927a280889c8c680c69' 
  AND token = '7ZOzUsez0A+4RIzLYLLSxkd0jW0+MC7UYqhmtmjagLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}