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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '197425f0c0fc9060d4e154cb32f0ed1e00c2ef375c0f1d72fc977ae1c0496667' 
  AND token = '2HvMp9Dbmk7+3BygGtkolWQ4kEpautzZysMvW7v3WV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}