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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34af70a070836c6c81dadaa3a71fbefb8c12ca5225840b2131a34df34f0e0207' 
  AND token = 'zn7ITW/n0c1gpW3Y/sICqTuHWw1i+quRNod5bFH4l8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}