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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8854503f4fd5aaf303c1bfacbd4710cca0317a795ae265136ac78407aec05d55' 
  AND token = 'cA7m4Xhr2Hh/Fcwg19iUBvmaDOVI88sZ8MLXY7yY1JM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}