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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cacd89849dab49f801043081d9a672e4749a24fe34401ec0da9eeb4fa345152a' 
  AND token = 'YV+2N5gPO5DBI0p3j5zhdAeb9HpUho8ssAJ5E7e8TzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}