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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65048aa416d52c401f1d957ffd7a5784695026d36fc4cd3c2bb3737feca4708e' 
  AND token = '5oQyurW29jmCpZsU82YjYRcU5JeeHrxwoP1IPZcw+MM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}