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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c21bb5c0cf77ddc69c233282e304e218557c0a55180c670d7e726f95ca0ff74' 
  AND token = 'ifqkyX6DpAIE8IDU2i6a4C7uKr1yVACcyEpaNhDXzBE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}