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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d4e4b9263989321d81ec5d4f02ee981f22ab08c0aa8ebb3730c362207ebc0a1' 
  AND token = 'pjSBcbEYP5mAHBFAsCWoWu94sD/2+y1g4SSNsYunVWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}