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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2783be883faaffc3bea1418130532fa9d8e195d3ba56c03fced5e88374b8c6e9' 
  AND token = 'mT9Naa7Khzb6Km/vGxOdfQUT3yrxdhRv1tJE77gBgOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}