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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '410d0a769bfd3a1686eb08ea420bceb4a572a8cfe7ce841b2b6677fb2bb8d432' 
  AND token = 'Q+QKl/S7zandOGNUaVzqN1gXUQ6M/BxXJRdOnAtTxSc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}