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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fcb46f5c3e28603f00a6fdf3ec08372e39f34474bdc28001b0816ddf55fc61f6' 
  AND token = 'tZAnnly/XL7Vdi0b3SC9c+s5SAkbc6xbUr8fPqOCTkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}