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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78139ba8570cdd8785f4a16021adb139db738a87d4b43d470a3663ac448231f1' 
  AND token = 'ZajJ1fBpPMLjO1evDNvPp4FNA8eiGbTH3GYh4B8VB1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}