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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd7123abf817cda2cb8395a1e53b361eaf333e104ef484ba9cb8d6bfb807c73f' 
  AND token = 'zJ7JJl2MheTYR4uqPVZ8ZA7bm4JZv6qR6pFPHI65Dgc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}