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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a439b858a812e68b4b82a87d7dca1ddb30df0c73c2ba221f2947323074aacde4' 
  AND token = 'Y3B2d4sIcJcpdhT5dr0cE257UOZWQcmnD8SuKj91RKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}