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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6f318b11d8e4c38b70c9b75abb1bd01f5ec05e5341821ded2f8778cb6e90842' 
  AND token = 'Nkzml72B6wOynoF/TOHk2ROHDjCqLjh5T5E9FwBrWU8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}