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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a1b82375381172e1612287d91d4941b096abaea4cc4d96266eb2b0f322dd0a4' 
  AND token = 'L4DvstO0/qHtuGi/Yns5trqzj3qMWZsLLCT37lrH4ic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}