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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6f22be553e80d50316426b739bb344ab65c45cdd837776ee43a66f547709bd0' 
  AND token = 'AoESFO3hKjrkfbKCPj+kdH+JQGMXFqUedvaP1+Sw1o8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}