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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0392e67d39bd33471debb480b2eb52f8e82804b0f751447dc156c50383eceb10' 
  AND token = 'z+GTM0w1cx7KIkdziDaUFYAiE3OLSHvKCc3Vj3B57Y0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}