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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21bbde320c9deb55ee7177e8a3487fdaded72894c8b69759503e41b6669e1a88' 
  AND token = '7RYA0Apiocm01w9qMAtZlJ/skRyAjxUqOzIqrVhkKMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}