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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aaef7df5ff1b8b79eef132d94305f028169d62fa5c78eb3f64e7aa17ab6c92d4' 
  AND token = 'rCbGDO0mBNNu6oaWP7TGlARtAbKwX+VIwyynwO0cR9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}