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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22e808926d7d50d948c9f71cbe982615f5ab0ef11d4b036e9d3185d2d9b578a5' 
  AND token = 'MhXY2+58HJJtcwHTN1UcR2gclhvmxrxNCssSxLyrHTU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}