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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f654fd3d657b064242232ae180aacc666410d3c1a434f64a16968fcf4bb5cfc' 
  AND token = 'N6EPGQp1Athe8ETr19/4c33MFS8vYlMzxh6GcYVPDtQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}