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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a66679e4a177c02bc3f93e46c4bc09fd913172aadadfacb661b5b95488c0451f' 
  AND token = 'DGx4ofN0kZpMilLbQNvHAn2tQ6Fo2NvaINrCB/Uhuoo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}