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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a3218b0b8b8b921516ad0f79c111daab250a930146278a59c8238e87a279a51' 
  AND token = 'TQywJ4uCRQFa0bvvQ3U4ckMmiogr6Gf5cxayhXEC8kI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}