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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf99f647cd5ae1a4867feefb122f281ab3b993f62c36f8b7f6782c481b5520e5' 
  AND token = 'XPxVZ2ClAAV12tWZVD1f4xyqWBq3NcxuauXpjG2Kqoo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}