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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a50998e3b4ef9cafdb11ebc98a2c0ac3b0697ac7c38fb3e75a48e53a9f19421' 
  AND token = 'O9G8gilo7luS1qz+b7JPFM3zMDhT8F7VjU0JGNArHHY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}