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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4394f8393dd8dac6bd5b69844f71cf06810b2c40ac163b75b32f5a2d27146c0f' 
  AND token = 'jerQaiwSUT5eb1UMRs20h+R1dam23aSNV5PH6pjvTGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}