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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4688853fbea9708eb0affc02f2585a5b12f6f56ec8d55ebb1f022085b5adfbc' 
  AND token = 'WKzWpxDZF4l8gPYrPDjmt3DDr6NeGzDt12CmfuaJP9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}