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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25dc153e1bfca0fd5098b168f661babc143f429f97fffc201ad01a9958e4019c' 
  AND token = 'ro2ntPIath66Jf+dH75Al7IFfqgn2OUMFbmXTUMC1Uk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}