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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc6f8cb769a919ac4c3a1db5ee6e82f712d11eb5724fa34acf075b110d1dece3' 
  AND token = 'QUOaXYZQodTeI/A+0ok0g9NtsWSPxKwKRaR4gNA6eDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}