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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3ca9777657ebb30d9ee4ce6b5dc80e667f4cc9a58582f155c61c115c2d6c630' 
  AND token = 'NfKp7JE+odReGrRmRFF/tPEhc1+hFdJwVubuiaBXjYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}