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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2018663d91bf1a9940659527f4222025e83c30f51c1de9d98797553669dbdc50' 
  AND token = 'spwHNtFzHKbhlOw7s0stnHel9A+Xe2N2c6TXk9QLwnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}