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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c57f3dbe982807d7d8f90764c16d9e787d7feee4354e36177ae672715ccb25e' 
  AND token = 'jHODwcFIfTWPsVz2U54ENjB6aW4LgvHQ/+/yaxkzUlk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}