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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc5d79c175dd30b9b08475c65c508014aec12fac6f383f0380d5ce097e9a0015' 
  AND token = 'jqW4v5EYaSqwn48aW7qSepJHXgj5OQGOCzbBCAbsGO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}